Roshan Kumar Dubey1, Satyam Shukla2*, Zeashan Hussain3, Mohammad Tasin4
1Department of Pharmaceutics, Mahatma Gandhi Institute of Pharmacy, Lucknow, Uttar Pradesh, India
2Department of Pharmacology, Mahatma Gandhi Institute of Pharmacy, Lucknow, Uttar Pradesh, India
3Department of Pharmacognosy, Mahatma Gandhi Institute of Pharmacy, Lucknow, Uttar Pradesh, India
4B. Pharm Students, Mahatma Gandhi Institute of Pharmacy, Lucknow, Uttar Pradesh, India
*Correspondence Author:
Satyam Shukla
Assistant Professor in the Department of Pharmacology, Mahatma Gandhi Institute of Pharmacy, Lucknow, Uttar Pradesh, India
Abstract
Madagascar periwinkle (Catharanthus roseus) is a plant species known for its rich pharmacological and phytochemical properties. This systematic review aims to comprehensively evaluate the potential of Madagascar periwinkle as a dietary supplement. A thorough search of relevant databases yielded studies focusing on the pharmacological activities and phytochemical constituents of Madagascar periwinkle. The review highlights the diverse pharmacological effects of Madagascar periwinkle, including anti-cancer, anti-diabetic, anti-inflammatory, and antimicrobial properties, among others. Furthermore, the phytochemical analysis revealed the presence of various bioactive compounds such as alkaloids, flavonoids, terpenoids, and phenolics, which contribute to its medicinal properties. Despite the promising findings, further research is warranted to elucidate the mechanisms of action, safety profile, and potential interactions of Madagascar periwinkle as a dietary supplement. Overall, this systematic review provides valuable insights into the pharmacological and phytochemical profiles of Madagascar periwinkle, suggesting its potential as a natural dietary supplement with diverse health benefits.
Keywords Madagascar periwinkle, Dietary supplement, Anti-cancer, Anti-diabetic, Anti-inflammatory
