Roshan Kumar Dubey1*, Satyam Shukla2, Zeashan Hussain3
1Department of Pharmaceutics, Mahatma Gandhi Institute of Pharmacy, Lucknow, Uttar Pradesh, India
2Department of Pharmacology, Mahatma Gandhi Institute of Pharmacy, Lucknow, Uttar Pradesh, India
3Department of Pharmacognosy, Mahatma Gandhi Institute of Pharmacy, Lucknow, Uttar Pradesh, India
* Address for Correspondence:
Roshan Kumar Dubey
Assistant Professor in the Department of Pharmaceutics, Mahatma Gandhi Institute of Pharmacy, Lucknow, Uttar Pradesh, India
Email ID – pharmaroshan95@gmail.com
Abstract
Silver nanoparticles (AgNPs) have garnered significant attention in recent years due to their unique properties and diverse applications across various industries. This review provides an overview of the synthesis methods, characterization techniques, applications, regulatory guidelines, and challenges associated with AgNPs. Green synthesis routes, utilizing natural extracts or biomolecules, have emerged as environmentally sustainable alternatives for producing AgNPs with reduced environmental impact. Characterization techniques such as spectroscopy, microscopy, and chromatography are employed to analyze the physicochemical properties of AgNPs and ensure their quality and stability. AgNPs find applications in biomedical, environmental, and consumer product sectors, including wound dressings, water purification filters, cosmetics, and medical devices, owing to their antimicrobial, catalytic, and optical properties. Regulatory guidelines play a crucial role in ensuring the safe and responsible use of AgNPs, addressing concerns related to biocompatibility, toxicity, and environmental impact. However, challenges remain in standardization, scalability, and long-term safety assessment of AgNP-based products. Future research efforts should focus on optimizing synthesis methods, enhancing characterization techniques, and addressing regulatory gaps to unlock the full potential of AgNPs while ensuring their safety and sustainability. Overall, AgNPs offer promising opportunities for addressing global challenges and driving technological innovation across diverse sectors.
Keywords Silver nanoparticles, Green synthesis, Plant extracts, Microorganisms, Characterization, Biomedical applications, Environmental remediation, Catalysis