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A Comprehensive Review: Personalized Medicine for Rare Disease Cancer Treatment
浏览量 226 时间 2024-06-04 08:51:45

Dr. Dharmendra Singh Rajput1* , Dr. Naveen Gupta2, Shubham Singh3, Bhawna Sharma3

1Professor, Patel College of Pharmacy, Madhyanchal Professional University, Ratibad, Bhopal, MP. India

2Professor and Dean, Patel College of Pharmacy, Madhyanchal Professional University, Ratibad, Bhopal, MP. India

3Ph.D. Research Scholar, Patel College of Pharmacy, Madhyanchal Professional University, Ratibad, Bhopal, MP. India


* Address    for  Correspondence:

Dr. Dharmendra Singh Rajput (Professor)

Patel College of Pharmacy, Madhyanchal Professional University, Ratibad,  Bhopal, MP. India.

Email – dsr141@gmail.com, singhrbgj@gmail.com  

ORCID - https://orcid.org/0009-0008-6569-3393


Abstract

In the United States, cancer is one of the major causes of death. In 2010 alone, over 1.5 million fresh instances were recorded and over 0.5 billion died. After the completion of human genome sequence, significant progress in characterizing human epigenomes, proteomes and metabolomes has been made; a stronger knowledge of pharmacogenomics has been established and the capacity for individual personalization of health care has grown considerably. Personalized medicine has recently been primarily used to systematically select or optimize the prevention and therapeutic care of the patient through genetic or other data about the particular patient. Molecular profiling in healthy samples and cancer patients can allow for more personalized medications than is currently available. Patient protein, genetic and metabolic information may be used for adapting medical attention to the needs of that individual. The development of complementary diagnostics is a key attribute of this medicinal model. Molecular tests measuring the level of proteins, genes or specific mutations are used to provide a specific treatment for a particular individual by stratify the status of a disease, selecting the right drugs and tailoring dosages to the particular needs of the patient. These methods are also available for assessing risk factors for a patient for a number of conditions and for tailoring individual preventive therapies. Recent advances of personalized cancer medicine, challenges and futures perspectives are discussed.

Keywords  Personalized medicine, Type, Cancer treatment

PDF A Comprehensive Review: Personalized Medicine for Rare Disease Cancer Treatment.pdf