Shubham Singh^1*, Dharmendra Singh Rajput², Naveen Gupta², Bhawna Sharma², Sanjesh Rathi¹, Arjun Singh³

¹School of Pharmacy, Rai University, Ahmedabad, Gujarat, India

²Patel College of Pharmacy, Madhyanchal Professional University, Bhopal, MP, India

³CSM Group of Institutions ( Faculty of B.Pharmacy), Prayagraj U.P. India

* Address    for  Correspondence:

Shubham Singh,

School of Pharmacy, Rai University, Ahmedabad, Gujarat, India

Abstract

Transdermal drug delivery system was presented to overcome the difficulties of drug delivery especially oral route. A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream. It promotes healing to an injured area of the body. An advantage of a transdermal drug delivery route over other types of delivery system such as oral, topical, i.v., i.m., etc. is that the patch provides a controlled release of the medication into the patient, usually through either a porous membrane covering a reservoir of medication or through body heat melting thin layers of medication embedded in the adhesive. The main disadvantage to transdermal delivery systems stems from the fact that the skin is a very effective barrier, as a result, only medications whose molecules are small can easily penetrate the skin, so it can be delivered by this method. This review article describes the overall introduction of transdermal patches including type of transdermal patches, method of preparation of transdermal patches and factor affecting etc.

Keywords  Transdermal drug delivery system; Hydrin rubber; Silicon rubber; Polyvinylalcohol; Transdermal patch; Polyvinylchloride; Di-N- butylphthalate; Triethylcitrate

PDF  A Brief Review on Transdermal Patches.pdf